HepHIV 2021 will be hosted in Lisbon and through a virtual conference platform and will consist of a mixture of plenary, parallel and e-poster sessions, side-meetings and e-exhibitions. The scientific content of the parallel and e-poster sessions is based on submitted abstracts, reviewed and selected by a group of independent reviewers, selected based on their scientific expertise and declaration of conflicting interests. All plenaries and panels will be moderated by two representatives: one from an institutional organisation (policy, academia or international institution) and one from a community/civil society organisation.